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Tyrosinase Primary Antibodies

Tyrosinase Novocastra

Malignant melanoma: immunohistochemical staining with Bond ready-to-use Tyrosinase (T311) using Bond Polymer Refine Detection.
Malignant melanoma: immunohistochemical staining with Bond ready-to-use Tyrosinase (T311) using Bond Polymer Refine Detection.

Antigen Background

The biosynthesis of melanin in melanocytes involves a family of enzymes, a key member of which is tyrosinase. Tyrosinase deficiency is associated with various forms of albinism and in particular oculocutaneous albinism. L-tyrosinase is the initial substrate for melanin biosynthesis and its conversion to dopaquinone is catalyzed by tyrosinase, whose expression is reported in melanocytes and melanomas.

 

 


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