Warning! You won't be able to use the quotation basket until you enable cookies in your Web browser.
Warning! Your Web browser is no longer supported. Please upgrade to a modern browser.
PD-L1 Reference Range

PD-L1

Non-small cell lung cancer, stained with PD-L1 BOND Ready-to-Use Primary Antibody (73-10), PA0832.
Non-small cell lung cancer, stained with PD-L1 BOND Ready-to-Use Primary Antibody (73-10), PA0832.

Antigen Background

Programmed death-ligand 1 (PD-L1), CD274 or B7 Homolog 1(B7-H1) is a protein encoded by the CD274 gene. When bound to its ligands, PD-1 and B7.1, it plays an immunosuppressive role by inhibiting T-cell activity. Overexpression of PD-L1 by cancer cells may enable them to evade the host immune response, conferring a growth advantage to such tumours. PD-L1 expression levels detected by immunohistochemistry can therefore be of prognostic value in some types of cancer.

 

PD-L1 is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using nonimmunologic histochemical stains.


loading...
Some products are not available in your region, please contact your Leica Biosystems representative to find a solution that is right for you.