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Multiplexing is an important tool for simultaneous detection of multiple markers within a single tissue section. These educational infographics highlight the 5 key reasons to multiplex, as well as the main considerations for choosing chromogenic or immunofluorescent detection.

Delivering Excellence in IHC, ISH and Fluorescent Tissue-Based Research including Multiplex Whole Slide Scanning The Aperio VERSA is a comprehensive digital pathology scanner, designed and developed to support the diverse imaging needs of cutting edge research facilities. The combination scanner is optimized for precision scanning of brightfield and fluorescent samples, with the accuracy and resolution required for FISH . From tissue-based and proteomic markers, to subcellular, molecular and in-situ hybridization probes, the Aperio VERSA delivers high-resolution, reliable imaging. Users can create a permanent record of their research – even faint fluorescent samples, which are often subject to fading. The Aperio VERSA is ideal for scanning multiplex slides at any magnifica...

This programmable system automates the denaturation and hybridization steps in slide-based FISH procedures, and provides walk-away convenience for technical personnel. The low cost unit accepts a wide range of sample types, is easy to use, and reduces hands-on time while ensuring overall precision and accuracy in FISH assays.

The Leica HER2 FISH System for BOND combines PathVysion®* LSI® HER2/CEP17® FISH probes (supplied by Abbott Molecular Inc.) and advanced BOND automation. Now laboratories, pathologists, and ultimately patients can benefit from easy and accurate FISH assessment of HER2 gene status in breast cancer tissue. Easy - eliminate manual complexity and increase standardization through automation Efficient - create a Lean workflow with single or batched cases Accurate – deliver accurate results for high diagnostic confidence

The Bond Oracle HER2 IHC System is a fully-automated assay to accurately determine HER2 oncoprotein status in breast cancer tissue as an aid in the assessment of patients for whom Herceptin® (trastuzumab) treatment is being considered. Accurate - optimized to precisely separate 1+ and 2+ cases gives you excellent FISH concordance, reducing avoidable FISH requests. Drive Consistency - standardized protocols for uniform staining, decreased process variation, and consistent results. Maximize Efficiency - full automation frees up your skilled staff for other high-value tasks. A Complete Solution - integrated ready-to-use reagents, control slides, and advanced automation ensure quality and consistency.

San Diego, CA – November 8, 2022. Leica Biosystems, a technology leader in automated staining and brightfield and fluorescent imaging, has acquired Cell IDx, Inc., a leader in multiplexed tissue profiling. Founded in 2012 and headquartered in San Diego, California, Cell IDx provides multiplex staining panels, tissue staining, and imaging and analysis services. Cell IDx’s UltraPlex technology allows simultaneous detection of multiple biomarkers in many immunoassays through fluorescent and chromogenic multiplex immunohistochemistry (“IHC”) staining technology, and automated chromogenic detection of multiple markers on Leica Biosystems’ BOND RX fully automated research stainer. Together, UltraPlex and BOND RX with high throughput imaging allows researchers to detect three or more ...

Flexible Image Analysis Platform for Every Cytogenomics Laboratory The CytoInsight GSL automated image analysis and case management system is a comprehensive Cytogenomics solution that improves quality and turnaround time from acquisition to analysis while reducing hands-on time at every step in your process. The CytoInsight GSL system improves image processing, provides system flexibility, and offers increased cybersecurity to deliver the tools to build your system to fit your Cytogenomics lab workflow. From prepared slide to report and back, the CytoInsight GSL flexible platform for brightfield and fluorescence image analysis provides unlimited scanning for a walk-away solution to meet the evolving needs of your Cytogenomics laboratory.