18 result(s) for 'CD8'
1 - 10 of 18 results for 'CD8'
Sort by
Show
Antigen Background
The CD8 molecule is composed of two chains and has a molecular weight of 32 kD. It is found on a T cell subset of normal cytotoxic/suppressor cells which make up approximately 20-35% of human peripheral blood lymphocytes.The CD8 antigen is reported to be detected on natural killer cells, 80% of thymocytes, on a subpopulation of 30% of peripheral blood null cells and 15-30% of bone marrow cells.
Disclaimer
CD8 is recommended for...
DESCRIPTION: Chromogenic multiplex IHC kit for BOND RX - human PD-L1, CD8, PanCK
SIZE: 10 slides
PRODUCT OVERVIEW: Kit for chromogenic multiplex IHC staining of 10 slides plus a single negative control slide on the BOND RX with V7.0 software.
1° Antibody
Clone
1° Tag
2° Antibody
Chromogen
PD-L1
73-10
UT014
Anti-UT014-HRP
Leica Blue
CD8
EPR10640(2)
UT015
Anti-UT015-AP
Leica Refine Red
PanCK
AE1/AE3
UT016
Anti-UT016-HRP
Yellow
Leica Ref...
DESCRIPTION: Chromogenic multiplex IHC kit for BOND RX - human CD4, CD8, PanCK
SIZE: 10 slides
PRODUCT OVERVIEW: Kit for chromogenic multiplex IHC staining of 10 slides plus a single negative control slide on the BOND RX with V7.0 software.
1° Antibody
Clone
1° Tag
2° Antibody
Chromogen
CD4
EPR6855
UT014
Anti-UT014-HRP
Leica Blue
CD8
EPR10640(2)
UT015
Anti-UT015-AP
Leica Refine Red
PanCK
AE1/AE3
UT016
Anti-UT016-HRP
Yellow
Leica Refin...
DESCRIPTION: Kit for fluorescent multiplex IHC staining of human CD3, CD4, CD8, FoxP3, detection with 490, 550, 650, 750 nm fluors
SIZE: 5 slides
PRODUCT OVERVIEW: All components required to stain 5 multiplex slides plus a single negative control slide with simple two-step protocol.
1° Antibody
Clone
1° Tag
2° Antibody
2° Fluor
CD3
CAL57
UT016
Anti-UT016
CL650
CD4
EPR6855
UT019
Anti-UT019
CL750
CD8
EPR10640(2)
UT015
Anti-UT015
CL490
Fo...
DESCRIPTION: Kit for fluorescent multiplex IHC staining of human CD3, CD4, CD8, CD20, detection with 490, 550, 650, 750 nm fluors
SIZE: 5 slides
PRODUCT OVERVIEW: All components required to stain 5 multiplex slides plus a single negative control slide with simple two-step protocol.
1° Antibody
Clone
1° Tag
2° Antibody
2° Fluor
CD3
CAL57
UT016
Anti-UT016
CL650
CD4
EPR6855
UT014
Anti-UT014
CL550
CD8
EPR10640(2)
UT015
Anti-UT015
CL490
CD2...
DESCRIPTION: Kit for fluorescent multiplex IHC staining of human CD8, CD68, Pan-CK, PD-L1, detection with 490, 550, 650, 750 nm fluors
SIZE: 5 slides
PRODUCT OVERVIEW: All components required to stain 5 multiplex slides plus a single negative control slide with simple two-step protocol.
1° Antibody
Clone
1° Tag
2° Antibody
2° Fluor
CD8
EPR10640(2)
UT015
Anti-UT015
CL490
CD68
C68/684
UT019
Anti-UT019
CL750
Pan-CK
AE1/AE3
UT016
Anti-UT016
...
DESCRIPTION: Kit for fluorescent multiplex IHC staining of human CD8, CD68, PD-1, PD-L1, detection with 490, 550, 650, 750 nm fluors
SIZE: 5 slides
PRODUCT OVERVIEW: All components required to stain 5 multiplex slides plus a single negative control slide with simple two-step protocol
1° Antibody
Clone
1° Tag
2° Antibody
2° Fluor
CD8
EPR10640(2)
UT015
Anti-UT015
CL490
CD68
C68/684
UT019
Anti-UT019
CL750
PD-1
EPR4877
UT016
Anti-UT016
CL650...
DESCRIPTION: Kit for fluorescent multiplex IHC staining of human CD4, CD8, FoxP3, PD-1, detection with 490, 550, 650, 750 nm fluors
SIZE: 5 slides
PRODUCT OVERVIEW: All components required to stain 5 multiplex slides plus a single negative control slide with simple two-step protocol.
1° Antibody
Clone
1° Tag
2° Antibody
2° Fluor
CD4
EPR6855
UT019
Anti-UT019
CL750
CD8
EPR10640(2)
UT015
Anti-UT015
CL490
FoxP3
1054C
UT014
Anti-UT014
CL550
...
It’s Time for TIME Alexander “Sandy” Borowsky Professor of Pathology and Laboratory Medicine Center for Immunology and Infectious Diseases
Disclosures Bristol-Meyers Squibb/Celgene: Funded through Investigator Sponsored Research (ISR) program. Discovery proposal. Leica/Aperio: Funded to run the “Genesis” study for primary diagnosis from whole slide images. Honorarium for this presentation. Histolix: Slide-free histology (Levenson and Fereidouni). Pfizer: Pfizer Protocol A9001502, Treatment Resistance Following Therapies (TRANSLATE) site PI. Agenda: In contracting to join the “FLEX” registry. None of these has actually paid me, only funding for the research projects.
Objectives • Introduction into the complexity of the TIME and the development of new cancer treatments though di...
Phenotyping Tumor Microenvironment Using DNA Barcoded Multiplex Technology Chifei Sun GSK IVIVTBIBCellular Biomarkers Collegeville, PA
I have no conflict of interests with Leica Biosystems, Ultivue and Indica Labs. – All the materials used in this presentation are for educational purpose only. – The human biological samples were sourced ethically, and their research use was in accord with the terms of the informed consents under an IRB/EC approved protocol. Statement 9/25/2020 2
Understand the complexity of tumor microenvironment and its importance in drug development – Introduce the Ultivue DNA barcoding and exchange technology for multiplex immunofluorescence – Highlight the processes of image fusion, spatial analysis and colocalization of markers on individual cells Learning...