MyoD1 (Rhabdomyosarcoma Marker) Primary Antibodies

MyoD1 (Rhabdomyosarcoma Marker)

Human rhabdomyosarcoma: immunohistochemical staining for MyoD1 protein using NCL-MyoD1. Note staining of a proportion of tumor cell nuclei. Paraffin section.
Human rhabdomyosarcoma: immunohistochemical staining for MyoD1 protein using NCL-MyoD1. Note staining of a proportion of tumor cell nuclei. Paraffin section.

Antigen Background

The murine MyoD1 gene encodes a phosphoprotein of 45 kD, the function of which may include the commitment, differentiation and maintenance of the myogenic lineage. MyoD1 is not expressed in normal adult tissue but is reported to be highly expressed in rhabdomyosarcomas.

Product Specific Information

NCL-L-MyoD1 recognizes an epitope near the C-terminus of the MyoD1 protein (amino acids 180 to 189)