CD5 Primary Antibodies

CD5 Novocastra

Human mantle cell lymphoma: immunohistochemical staining for CD5 antigen using  NCL-CD5-4C7. Note intense membrane staining of tumor cells. Paraffin section.
Human mantle cell lymphoma: immunohistochemical staining for CD5 antigen using NCL-CD5-4C7. Note intense membrane staining of tumor cells. Paraffin section.

Antigen Background

CD5 antigen is reported to be expressed on 95 percent of thymocytes and 72 percent of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed on T cells. CD5 antigen is also expressed by many T cell leukemias, lymphomas, activated T cells and on a subset of B cells located primarily in the mantle zones of normal lymph nodes. CD5 antigen expression is also reported in T cell acute lymphocytic leukemias (T-ALL), some B cell chronic lymphocytic leukemias (B-CLL) as well as B and T cell lymphomas.