Progesterone Receptor Primary Antibodies

Progesterone Receptor

Breast carcinoma, nuclear staining in a proportion of tumor cells. Paraffin section.
Breast carcinoma, nuclear staining in a proportion of tumor cells. Paraffin section.

Antigen Background

The human progesterone receptor (PR) is expressed as two isoforms, PRA (94 kD) and PRB (114 kD), which function as ligand-activated transcription factors. These two isoforms are transcribed from distinct estrogen receptor (ER)-inducible promoters within a single copy PR gene.

The PRA form is a truncated version of the PRB form, lacking the first 164 N-terminal amino acids. In humans, PRA acts as a transdominant repressor of the transcriptional activity of PRB, glucocorticoid receptor, ER, androgen receptor and mineralocorticoid receptor.PRB functions mainly as a transcriptional activator. PRB is expressed strongly in endometrial glandular and stromal nuclei in the proliferative phase of the menstrual cycle and weakly during the secretory phase and early pregnancy.

Product Specific Information

Clone 16 is specific for a region of the N-terminus of the A form of PR. The precise epitope has not been mapped but it reacts with both A and B forms of PR by Western blot but only with the A form by immunohistochemistry. This suggests that the epitope is inaccessible in the native folded B form of the protein.


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CLONE: 16

Material with code "PR" is discontinued , possible alternatives:

在这里订购产品

代码 名称 Configuration Use Datasheet MSDS 数量
PA0312 7ml PR Bond RTU Primary Bond ready to use reagent P(HIER) MSDS 1
PGR-312-L-CE 1ml NCL-L-PGR-312 Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS 1
PGR-312-L-CN NCL-L-PGR-312 Liquid Concentrated Monoclonal Antibody P(HIER) MSDS 1
PGR-312-L 1ml NCL-L-PGR-312 Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS 1
PGR-312-L-S 0.1ml NCL-L-PGR-312 Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS 1
PGR-312-L-F 1ml NCL-L-PGR-312 Class II Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS 1
PGR-312-L-CE-S 0.1ml NCL-L-PGR-312 Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS 1
PGR-312/2-L 2ml NCL-L-PGR-312/2 Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS 1
PGR-312/2-L-CE 2ml NCL-L-PGR-312/2 Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS 1
PGR-312-S 0.1ml NCL-PGR-312 Lyophilised Concentrated Monoclonal Antibody P(HIER) Info MSDS 1
PGR-312-CE 1ml NCL-PGR-312 Lyophilised Concentrated Monoclonal Antibody P(HIER) Info MSDS 1
PGR-312-F 1ml NCL-PGR-312 Class II Lyophilised Concentrated Monoclonal Antibody P(HIER) Info MSDS 1
PGR-312/2-CE 2ml NCL-PGR-312/2 Lyophilised Concentrated Monoclonal Antibody P(HIER) Info MSDS 1
PGR-312/2 2ml NCL-PGR-312/2 Lyophilised Concentrated Monoclonal Antibody P(HIER), W Info MSDS 1
PGR-312-F-S 0.1ml NCL-PGR-312 Class II Lyophilised Concentrated Monoclonal Antibody P(HIER) Info MSDS 1
PGR-312 1ml NCL-PGR-312 Lyophilised Concentrated Monoclonal Antibody P(HIER) Info MSDS 1
PGR-312-CE-S 0.1ml NCL-PGR-312 Lyophilised Concentrated Monoclonal Antibody P(HIER) Info MSDS 1
PGR-312-O-F ORG-8721 - 7ml PGR-312 Class II Origin P Info MSDS 1
PGR-312-R-7-CE 7ml RTU-PGR-312 Ready to Use Monoclonal Antibody P(HIER) Info 1
PGR-312-R-7 7ml RTU-PGR-312 Ready to Use Monoclonal Antibody P(HIER) Info 1
PGR-312-R-7-F 7ml RTU-PGR-312 Class II Ready to Use Monoclonal Antibody P(HIER) Info 1

CLONE: 1A6

Material with code "PR" is discontinued , possible alternatives:

在这里订购产品

代码 名称 Configuration Use Datasheet MSDS 数量
PGR-L-CE 1ml NCL-L-PGR Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS 1
PGR-2 2ml NCL-PGR/2 Lyophilised Concentrated Monoclonal Antibody P(HIER), W Info MSDS 1
PGR 1ml NCL-PGR Lyophilised Concentrated Monoclonal Antibody P(HIER) Info MSDS 1
PGR-2-CE 2ml NCL-PGR/2 Lyophilised Concentrated Monoclonal Antibody P(HIER) Info MSDS 1
PGR-CE 1ml NCL-PGR Lyophilised Concentrated Monoclonal Antibody P(HIER) Info MSDS 1
PGR-R-7 7ml RTU-PGR Ready to Use Monoclonal Antibody P(HIER) Info 1
PGR-R-7-CE 7ml RTU-PGR Ready to Use Monoclonal Antibody P(HIER) Info 1
Material with code "PR" is discontinued , possible alternatives:

在这里订购产品

代码 名称 数量
PGRP 0.2ml NCL-PGRp 1