ALK Primary Antibodies

ALK

Human anaplastic lymphoma: immunohistochemical staining for anaplastic lymphoma kinase (p80) using NCL-ALK. Note cytoplasmic staining of large pleomorphic cells. Paraffin section.
Human anaplastic lymphoma: immunohistochemical staining for anaplastic lymphoma kinase (p80) using NCL-ALK. Note cytoplasmic staining of large pleomorphic cells. Paraffin section.

Antigen Background

Anaplastic large cell lymphoma (ALCL) is usually composed of large pleomorphic cells which are reported to express CD30 antigen and the epithelial membrane antigen (EMA).These tumor cells tend to occur in younger individuals and may be associated with cutaneous and extranodal involvement. A proportion of these cases contain a chromosomal translocation t(2;5) (p23;q35).This results in a hybrid gene encoding part of the nucleophosmin (NPM) gene joined to the cytoplasmic domain of the anaplastic lymphoma kinase (ALK) gene, giving rise to the protein, p80.Large cell lymphomas account for approximately 25 percent of all non-Hodgkin's lymphomas in children and young adults, of which one third carries the NPM-ALK gene translocation.


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CLONE: 5A4

Material with code "ALK" is discontinued , possible alternatives:

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代码 名称 Configuration Use Datasheet MSDS 数量
PA0831 7 mL ALK (5A4) BOND RTU Primary Bond ready to use reagent P(HIER) Info MSDS 1
PA0306 7ml ALK Bond RTU Primary Bond ready to use reagent P(HIER) Info MSDS 1
ALK-L-H 0.5ml NCL-L-ALK Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS 1
ALK-L-S 0.1ml NCL-L-ALK Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS 1
ALK-L-CE-H 0.5ml NCL-L-ALK Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS 1
ALK-L-CE-S 0.1ml NCL-L-ALK Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS 1
ALK-S 0.1ml NCL-ALK Lyophilised Concentrated Monoclonal Antibody P(HIER) Info MSDS 1
ALK 1ml NCL-ALK Lyophilised Concentrated Monoclonal Antibody P(HIER) Info MSDS 1
ALK-CE 1ml NCL-ALK Lyophilised Concentrated Monoclonal Antibody P(HIER) Info MSDS 1
ALK-CE-S 0.1ml NCL-ALK Lyophilised Concentrated Monoclonal Antibody P(HIER) Info MSDS 1