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Fluorescence Microscopy

Superior optics, ergonomics, automation and image quality make Leica Biosystems your imaging solution provider of choice.

Leica Biosystems provides you with wide range of fluorescence imaging capabilities starting with fluorescence microscopes through dedicated integrated FISH capture stations, to FISH scanning solutions.

DM2000, DM2000 LED and DM4 B are perfect Immunofluorescence (IF) and manual FISH capture workstations for diagnostics/prognostics.

CytoVision DM2500 and DM5500 Capture systems are FISH capture workstations for diagnostics / prognostics.

Fully automated unattended cellular FISH capture of up to 120 slides with the CytoVision Platform and solid tumor FISH and immunofluorescence with the Ariol system.

Fluorescence Microscopy: Choose the microscope you need for routine fluorescence applications.

Select the DM2000 & 2000 LED system microscopes.

Select the DM4 B automated upright microscope system.


DM2000 & DM2000 LED

Advanced design, LED or 30W halogen illumination; full range of contrasting techniques.



Advanced automated design, LED illumination; full range of contrasting techniques.

Software capabilities

2D Analysis – Easy versatile wizard for 2D analysis of multi-dimensional datasets Workflow oriented design for maximum ease of use, enabling even novices to become productive with little training effort.

Select the DFC3000 G digital imaging camera for routine fluorescence documentation.

Select the DFC450 C digital camera routine fluorescence imaging.

DFC3000 G

Monochrome cooled 1.3MPixel CCD digital camera. USB 3.0; compatible with LAS/LAS-AF.

DFC450 C

Color cooled 5MPixel CCD digital camera. Firewire-B; compatible with LAS/LAS-AF; TWAIN interface.

Semi automated FISH capture stations

Select CytoVision DM2500 capture station

Select CytoVision DM5500 capture station

CytoVision Software

DM2500 Capture

Large capacity; automated filter wheel for ergonomic FISH scoring, capture and  documentation.

DM5500 Capture

Rapid fully automated single click capture of multi-channel, multi-plane FISH images.

Software capabilities

Automated, accurate FISH signal counting for all common assays
Simple manual scoring  or semi automated, multi-session scoring
Fast documentation, archiving and  case retrieval with the ultimate professional reports.

Automated Fluorescence Scanning

Select the CytoVision platform for cellular FISH analysis.

Select the Ariol System for solid tumour FISH analysis


The complete solution for cellular FISH scanning and analysis combined with efficient workflows to reduce sample reporting times. Ideal for the Cytogenetics laboratory.


Immunofluoresence and FISH scanning in tissue sections and TMA’s, combined with image analysis for quantitative assessment. Ideal for the Pathology clinical and research laboratory.

CytoVision Software

Ariol Software

Cytovision Software Capabilities

Unattended accurate FISH scanning, capture and analysis, that’s easy to use.

Automated oiling and Z-Stack capture for the best possible image quality and graphical cell sorting to find the cells you need to see.

Ariol Software Capabilities

Link brightfield and fluorescent serial sections to aid region of interest selection for scanning.

Flexible, powerful FISH scoring with fully automated DAPI segmentation.

Quantitaive algorithms for immunofluorescence.