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Human papillomaviruses (HPVs) are the etiologic agents for a significant fraction of many cancers in humans. Our understanding of the pathogenesis of these tumors has led to almost continuous refinement in our approach to managing patients at risk for these tumors. These refinements include improved testing strategies for both screening, triage, diagnosis and treatment. This presentation will update you on how our current understanding of HPV biology and testing provides our patients with medical care personalized to their biology and risk.
- Briefly review the biology of HPV in carcinogenesis.
- Describe the importance of clinically valid HPV testing in modern cervical cancer screening paradigms.
- Appreciate the clinical utility of HPV-related IHC and/or ISH in making a correct histologic diagnosis on cervical specimens.
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