http://www.leicabiosystems.com/pathologyleaders/tag/tags/antibody/show/tag/ Article tagged with Antibody en-US Stimulated Emission Depletion microscopy, or STED nanoscopy, is a technique that uses the non-linear de-excitation of fluorescent dyes to overcome the resolution limit imposed by diffraction encountered with standard confocal laser scanning microscopes and conventional far-field optical microscopes[1]. Compared to traditional confocal microscopy, STED offers exceptional improvements in resolution allowing visualization of cellular events at unprecedented levels. http://www.leicabiosystems.com/http://www.leica-microsystems.com/science-lab/subcellular-localization-of-akt-and-tubulin-using-super-resolution-microscopy/ Thu, 01 Dec 2011 00:00:00 +0100 Ph.D. Carl A. Ascoli, Ph.D. Myriam Gastard, Ph.D. David P. Chimento Folate Receptor-alpha (FR-alpha) has been described extensively in many tumour and tissue types. Up to now the majority of this work has been looking at mRNA with some limited immunohistochemistry restricted to frozen tissue. In this article we review the extensive testing undertaken to evaluate a novel mouse monoclonal antibody to FR-alpha that works in formalin-fixed paraffin-embedded tissue. http://www.leicabiosystems.com/pathologyleaders/evaluation-of-antibody-to-folate-receptor-alpha-fr-%CE%B1/ Mon, 31 May 2010 00:00:00 +0200 Paul Scorer, Ph.D. Nicola Lawson The North East Haematopathology Diagnostic Service, based at the Royal Victoria Infirmary in Newcastle upon Tyne, provides a regional service for expert assessment of lymphoproliferative and myeloproliferative disorders for a regional network of 14 NHS hospitals in the North East and Cumbria. http://www.leicabiosystems.com/pathologyleaders/prospective-evaluation-of-new-cd19-cd30-and-cd7-antibodies-for-fixed-tissue-immunohistology/ Mon, 10 May 2010 00:00:00 +0200 Ph.D. Gary McIntosh, Colin Tristram, Paul Scorer, Ph.D. Nigel Piggott, Stephen Cowell, G. Menon The increased sensitivity of immunohistochemistry (IHC) over standard Hematoxylin and Eosin (H&E) staining has established the IHC technique in the study of many diseases. Herein we describe the utility of some NovocastraTM antibodies that can be used in the study of brain and muscle diseases. http://www.leicabiosystems.com/pathologyleaders/brains-and-brawn-antibodies-in-research-and-diagnosis/ Mon, 07 Sep 2009 00:00:00 +0200 Ph.D. Nigel Piggott, Ph.D. Gary McIntosh CD11c is an integrin glycoprotein expressed by mononocytes and macrophages, neutrophils, myeloid dendritic cells and a small subset of lymphocytes. Although antibodies to CD11c have been available since the mid-1980s, the new antibody 5D11 is the first to recognise a formalin-resistant epitope. http://www.leicabiosystems.com/pathologyleaders/cd11c/ Wed, 01 Oct 2008 00:00:00 +0200 Wendy N. Erber Newcastle upon Tyne – this lively town in Northern England is not only famous for its culture, but it has been the base for the developer and manufacturer of antibodies and other reagents of the brand, Novocastra™. “Novocastra” is based upon the Latin name for the city of Newcastle and was the name given to the original company founded by Prof C. Wilson Horne. The company... http://www.leicabiosystems.com/pathologyleaders/from-concept-to-diagnosis-how-antibodies-are-designed/ Thu, 08 May 2008 00:00:00 +0200 Dr. Kenneth Mitchell