ArticleCD99: Development and Evaluation of a Novel Monoclonal Antibody for use in Manual and Automated ImmunohistochemistryCD99 is a transmembrane glycoprotein which is expressed in a wide range of tissues. Although its function is not fully understood it has been implicated in a variety of cellular processes including the homotypic aggregation of the T cells, apoptosis of immature thymocytes, up-regulation of T cell…
Article15. Sep 2007 Institute: University College London Hospital, UCL Advanced Diagnostics, Department of Pathology, London, UKWe at UCL Advanced Diagnostics were lucky enough to be involved in the external assessment of CD3, LN10 in its validation stage. This enabled us to begin using it routinely as soon as it was commercially available, indicating our feelings on it!
ArticleCD3 Mouse Monoclonal Antibodies, Assessment of the New Clone LN10 Against PS1: An Improvement on a Routine Tool for the Haematopathologist!15. Sep 2007 Institute: Charité Hospital, Institute of Pathology and Reference Center for Haematopathology, Berlin, GermanyCD3 is a reliable and specific marker for the detection of cells of the T-cell lineage and has been, therefore, routinely used by pathologists for many years. The PS1 clone was a great advancement when it was first released. It was robust and able to work in decalcified bone marrow trephines where…