Antibody

• Article
  Subcellular Localization of AKT and Tubulin using Super-Resolution Microscopy
  

  01. Dec 2011 Authors: Carl A. Ascoli, Ph.D. , Myriam Gastard, Ph.D. , David P. Chimento, Ph.D. Institutes: Leica Microsystems, Rockland Immunochemicals Inc., Philadelphia, Pennsylvania, USA

  Stimulated Emission Depletion microscopy, or STED nanoscopy, is a technique that uses the non-linear de-excitation of fluorescent dyes to overcome the resolution limit imposed by diffraction encountered with standard confocal laser scanning microscopes and conventional far-field optical… Read article
  
  
• Article
  Evaluation of Antibody to Folate Receptor-alpha (FR-α)
  

  31. May 2010 Authors: Paul Scorer, Nicola Lawson, Ph.D. Institute: Leica Biosystems, Wetzlar, Germany

  Folate Receptor-alpha (FR-alpha) has been described extensively in many tumour and tissue types. Up to now the majority of this work has been looking at mRNA with some limited immunohistochemistry restricted to frozen tissue. In this article we review the extensive testing undertaken to evaluate a… Read article
  
  
• Article
  Prospective Evaluation of New CD19, CD30 and CD7 Antibodies for Fixed Tissue Immunohistology
  

  10. May 2010 Authors: Gary McIntosh, Ph.D. , Colin Tristram, Paul Scorer, Nigel Piggott, Ph.D. , Stephen Cowell, G. Menon Institutes: Leica Biosystems, Wetzlar, Germany, Newcastle University, Newcastle upon Tyne Hospitals NHS Foundation Trust, UK, Northern Institute for Cancer Research (NICR), Newcastle, UK

  The North East Haematopathology Diagnostic Service, based at the Royal Victoria Infirmary in Newcastle upon Tyne, provides a regional service for expert assessment of lymphoproliferative and myeloproliferative disorders for a regional network of 14 NHS hospitals in the North East and Cumbria. Read article
  
  
• Article
  Brains and Brawn - Antibodies in Research and Diagnosis
  

  07. Sep 2009 Authors: Nigel Piggott, Ph.D. , Gary McIntosh, Ph.D. Institute: Leica Biosystems, Wetzlar, Germany

  The increased sensitivity of immunohistochemistry (IHC) over standard Hematoxylin and Eosin (H&E) staining has established the IHC technique in the study of many diseases. Herein we describe the utility of some NovocastraTM antibodies that can be used in the study of brain and muscle diseases. Read article
  
  
• Article
  CD11c
  

  01. Oct 2008 Author: Wendy N. Erber Institute: Addenbrooke's Hospital, Haematology Department, Cambridge, United Kingdom

  CD11c is an integrin glycoprotein expressed by mononocytes and macrophages, neutrophils, myeloid dendritic cells and a small subset of lymphocytes. Although antibodies to CD11c have been available since the mid-1980s, the new antibody 5D11 is the first to recognise a formalin-resistant epitope. Read article