Artifacts in Histological and Cytological Preparations01. April 2008
Histology artifacts and cytology artifacts are structures that were not originally present in the living tissue. These artifacts can be from a range of sources including contamination, poor tissue preparation and surgical procedures. Understanding artifacts is important for both histologists and pathologists as they have the potential to compromise accurate diagnosis.
Artifacts in Histological and Cytological Preparations describes many common histology and cytology artifacts and offers suggestions on their causes, and importantly how they can be avoided.
The artifact classification scheme is modified from that originally devised by Wallington1 and follows the standard histology and cytology sequences while also including some specialized techniques.