Myelin Basic Protein Novocastra
Myelin basic protein is reported to account for about 30 percent of the proteins in myelin found in the central nervous system. It can induce experimental allergic encephalomyelitis (EAE), a T-lymphocyte mediated disease due to delayed-type hypersensitivity; though each animal species appears to respond to a different fragment of the 170 amino acid polypeptide. Four different isoforms have been identified through cDNA cloning. All four of these variants are identical except for the insertion or deletion of two peptide fragments encoded by exons 2 and 5. Myelin basic protein is reported to be expressed in oligodendrocytes, myelin of white matter in the brain and spinal cord, and in peripheral nerves, though it is expressed less abundantly in gray matter.
Product Specific Information
NCL-MBP was raised to guinea pig myelin basic protein and is reactive with human myelin basic protein.
|MBP||1ml NCL-MBP||Lyophilised Concentrated Monoclonal Antibody||P(HIER)||Info||MSDS||1|
|MBP-S||0.1ml NCL-MBP||Lyophilised Concentrated Monoclonal Antibody||P(HIER)||Info||MSDS||1|