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Novocastra Muscle Specific Actin

Antigens Background

Actins are protein constituents of microfilaments, the ubiquitous cytoskeletal elements present in most cells.

Actins can be biochemically and immunologically divided into three main subsets; alpha-actins are present in muscle tissue, beta- and gamma-actins are present in non-muscle cells, with a minor subset of gamma-actins present in muscle cells.

NCL-MSA is specific for alpha- and gamma-actins of smooth muscle (42 kD) reported to be expressed in striated muscle fibers of the myocardium, skeletal muscle, arterial cell wall, smooth muscle coat of the entire gastrointestinal tract, myometrial smooth muscle, prostatic stroma and bladder wall.

Human prostate: immunohistochemical staining for muscle specific actin using NCL-MSA. Note cytoplasmic staining of smooth muscle cells in the stroma around the glands. Paraffin section.
Human prostate: immunohistochemical staining for muscle specific actin using NCL-MSA. Note cytoplasmic staining of smooth muscle cells in the stroma around the glands. Paraffin section.

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CLONE: HHF35

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Code Name Configuration Use Datasheet MSDS Qty
PA0258 7ml MuscSpecAct Bond RTU Prim Bond ready to use reagent P Info MSDS
MSA-L-U 1ml NCL-L-MSA Liquid Concentrated Monoclonal Antibody P Info MSDS
MSA-U 1ml NCL-MSA US IVD Lyophilised Concentrated Monoclonal Antibody F, P, W Info MSDS
MSA 1ml NCL-MSA Lyophilised Concentrated Monoclonal Antibody F, P, W Info MSDS

CLONE: SC28

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Code Name Configuration Use Datasheet MSDS Qty
MSA-594-L 1ml NCL-L-MSA-594 Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS
MSA-594-L-CE 1ml NCL-L-MSA-594 Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS