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Synaptophysin Primary Antibodies

Synaptophysin Novocastra

Breast carcinoma showing neuroendocrine differentiation: immunohistochemical staining for synaptophysin using NCL-SYNAP-299. Note cytoplasmic staining of tumor cells. Paraffin section.
Breast carcinoma showing neuroendocrine differentiation: immunohistochemical staining for synaptophysin using NCL-SYNAP-299. Note cytoplasmic staining of tumor cells. Paraffin section.

Antigen Background

Synaptophysin is an integral membrane glycoprotein with a molecular weight of 38 kD. It is reported to occur in presynaptic vesicles of neurons in brain, spinal cord, retina, in similar vesicles of the adrenal medulla as well as in neuromuscular junctions.

Synaptophysin may be involved in synaptic vesicle formation and exocytosis. Synaptophysin is reported to be expressed in a wide spectrum of neuroendocrine tumors including neuroblastomas, ganglioneuroblastomas, phaeochromocytomas, chromaffin and non-chromaffin paragangliomas.

Synaptophysin is also reported to be expressed in neuroendocrine tumors of epithelial type including pituitary adenomas, islet cell tumors, medullary carcinomas of thyroid, parathyroid adenomas, carcinoids of the bronchopulmonary and gastrointestinal tracts, neuroendocrine carcinomas of the bronchopulmonary and gastrointestinal tract and neuronendocrine carcinomas of the skin.


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CLONE: 27G12

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Code Name Configuration Use Datasheet MSDS Qty
PA0299 7ml Synaptoph Bond RTU Primary Bond ready to use reagent P(HIER) Info MSDS
SYNAP-299-L 1ml NCL-L-SYNAP-299 Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS
SYNAP-299-L-CE 1ml NCL-L-SYNAP-299 Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS
SYNAP-299-CE-S 0.1ml NCL-SYNAP-299 Lyophilised Concentrated Monoclonal Antibody P(HIER) Info MSDS
SYNAP-299 1ml NCL-SYNAP-299 Lyophilised Concentrated Monoclonal Antibody P(HIER) Info MSDS
SYNAP-299-S 0.1ml NCL-SYNAP-299 Lyophilised Concentrated Monoclonal Antibody P(HIER) Info MSDS
SYNAPP 1ml NCL-SYNAPp Lyophilised Polyclonal F, P(HIER) Info MSDS
SYNAP-299-O ORG-8848 - 7ml SYNAP-299-O Origin P Info MSDS