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Surfactant Precursor Protein B Primary Antibodies

Surfactant Precursor Protein B Novocastra

Human lung adenocarcinoma: immunohistochemical staining for surfactant precursor protein B using NCL-SPPB. Note cytoplasmic staining of Clara cells and extracellular protein. Paraffin section.
Human lung adenocarcinoma: immunohistochemical staining for surfactant precursor protein B using NCL-SPPB. Note cytoplasmic staining of Clara cells and extracellular protein. Paraffin section.

Antigen Background

Pulmonary surfactant is a phospholipid-rich mixture that reduces the surface tension at the alveolar air-liquid interface, providing alveolar stability necessary for normal ventilation.Four distinct proteins which have been isolated from pulmonary surfactant are SP-A, SP-B, SP-C and SP-D. Surfactant precursor protein B (pro-SP-B) with a molecular weight of 42 kD undergoes proteolytic processing resulting in a 9 kD non-collagenous hydrophobic pulmonary surfactant, SP-BSP-B mRNA has been detected in both type II cells and in bronchiolar epithelial cells of adult human, mouse, rat and rabbit lung. 


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CLONE: 19H7

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Code Name Configuration Use Datasheet MSDS Qty
SPPB-S 0.1ml NCL-SPPB Lyophilised Concentrated Monoclonal Antibody P(HIER) Info MSDS
SPPB-U 1ml NCL-SPPB US IVD Lyophilised Concentrated Monoclonal Antibody P(HIER) Info MSDS