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Retinoblastoma Gene Protein Primary Antibodies

Retinoblastoma Gene Protein Novocastra

Human tonsil: immunohistochemical staining for retinoblastoma gene protein using NCL-RB-358. Note intense nuclear staining of epithelial cells. Paraffin section.
Human tonsil: immunohistochemical staining for retinoblastoma gene protein using NCL-RB-358. Note intense nuclear staining of epithelial cells. Paraffin section.

Antigen Background

Retinoblastoma (Rb) is a rare tumor of the retina associated with mutations of chromosome 13. The nuclear phosphoprotein encoded by the Rb tumor suppressor gene is present in many cells and may indirectly regulate cell growth by activating the transcription factor ATF-2. Activation of ATF-2 initiates expression of TGF-β2, which in turn inhibits transcription of genes affecting cell growth. Bilateral mutation of the Rb gene may potentially play a role in the development of a number of malignant tumors.

Product Specific Information

NCL-RB-358 was raised to the N-terminal region of the Rb gene protein.


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CLONE: 13A10

Material with code "RetinoblastoGenePr" is discontinued , possible alternatives:

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Code Name Configuration Use Datasheet MSDS Qty
RB-358-L-U 1ml NCL-L-RB-358 US IVD Liquid Concentrated Monoclonal Antibody P(HIER), W Info MSDS
RB-358-L 1ml NCL-L-RB-358 Liquid Concentrated Monoclonal Antibody P(HIER), W Info
RB-358-S 0.1ml NCL-RB-358 Lyophilised Concentrated Monoclonal Antibody P(HIER), W Info MSDS
RB-358 1ml NCL-RB-358 Lyophilised Concentrated Monoclonal Antibody P(HIER), W Info MSDS

CLONE: 1F8

Material with code "RetinoblastoGenePr" is discontinued , possible alternatives:

Request a quote

Code Name Configuration Use Datasheet MSDS Qty
RB 1ml NCL-RB Lyophilised Concentrated Monoclonal Antibody P(HIER):W Info MSDS