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Oct-3/4 Primary Antibodies

Oct-3/4

Human seminoma: immunohistochemical staining for Oct-3/4 transcription factor using PA0193 (clone N1NK). Note intense staining of pluripotent tumor cells. Paraffin section.
Human seminoma: immunohistochemical staining for Oct-3/4 transcription factor using PA0193 (clone N1NK). Note intense staining of pluripotent tumor cells. Paraffin section.

Antigen Background

Oct3/4 is a member of the POU homeodomain family of transcription factors, which is expressed by embryonic stem cells and germ cells. A critical amount of Oct3/4 is required to maintain stem cell self replication. Down regulation of Oct3/4 levels are associated with loss of pluripotency. Oct3/4 has been proposed as a useful marker for germ cell tumors which exhibit features of pluripotentiality, including seminoma/dysgerminoma/germinoma and embryonal carcinoma, and establishing a germ cell origin for some metastatic tumors of uncertain primary tumor.


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CLONE: N1NK

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Code Name Configuration Use Datasheet MSDS Qty
PA0934 7ml Oct-3/4 Bond RTU Primary Bond ready to use reagent P(HIER) Info MSDS
PA0193 7ml Oct-3/4 (N1NK) Bond RTU Primary Bond ready to use reagent Info MSDS
OCT3/4-L-S 0.1ml NCL-L-OCT3/4 Liquid Concentrated Monoclonal Antibody P(HIER), W Info MSDS
OCT3/4-L 1ml NCL-L-OCT3/4 Liquid Concentrated Monoclonal Antibody P(HIER), W Info MSDS
OCT3/4-L-CE 1ml NCL-L-OCT3/4 Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS
OCT3/4-L-CE-S 0.1ml NCL-L-OCT3/4 Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS