Warning! You won't be able to use the quotation basket until you enable cookies in your Web browser.
Warning! Your Web browser is no longer supported. Please upgrade to a modern browser.
Nitric Oxide Synthase Antibodies Primary Antibodies

Nitric Oxide Synthase Antibodies Novocastra

Human small intestine: immunohistochemical staining for nitric oxide synthase-1 using  NCL-NOS-1. Note cytoplasmic staining of enteric ganglia. Paraffin section.
Human small intestine: immunohistochemical staining for nitric oxide synthase-1 using NCL-NOS-1. Note cytoplasmic staining of enteric ganglia. Paraffin section.

Antigen Background

Human nitric oxide synthases are a family of enzymes responsible for the synthesis of nitric oxide (NO) from L-arginine and molecular oxygen. There are at least three nitric oxide synthases; NOS-1, also known as neuronal NOS or nNOS, NOS-2, which is referred to as inducible NOS or iNOS and NOS-3, also known as endothelial NOS or eNOS. As suggested by their nomenclature, these enzymes have different cellular distribution and are subjected to different regulatory mechanisms. NOS-3 is reported to be constitutively expressed and produces picomolar quantities of NO which play a role in signal transmission resulting in physiological effects. In the gastrointestinal tract, NO is reported to play a protective role where it has direct microbiocidal properties and acts as a first line of mucosal defence in the stomach. The function of NO in tumor development, promotion and progression is unclear. The effects may be both beneficial but also detrimental to those individuals with gastric cancer, where it is reported that NO supports tumor progression through the creation of neovasculature.


loading...

CLONE: NOS-125

Material with code "NOS Abs" is discontinued , possible alternatives:

Request a quote

Code Name Configuration Use Datasheet MSDS Qty
NOS-1-L-U 1ml NCL-L-NOS-1 Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS
NOS-1 1ml NCL-NOS-1 Lyophilised Concentrated Monoclonal Antibody P(HIER) Info MSDS
NOS-1-U 1ml NCL-NOS-1 US IVD Lyophilised Concentrated Monoclonal Antibody P(HIER) Info MSDS

CLONE: RN5

Material with code "NOS Abs" is discontinued , possible alternatives:

Request a quote

Code Name Configuration Use Datasheet MSDS Qty
NOS-3 1ml NCL-NOS-3 Lyophilised Concentrated Monoclonal Antibody F, P(HIER) Info MSDS