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Myeloperoxidase Primary Antibodies

Myeloperoxidase Novocastra

Human bone marrow, granulocytic sarcoma: immunohistochemical staining for myeloperoxidase using NCL-MYELO. Note intense cytoplasmic staining of malignant myeloid cells. Paraffin section.
Human bone marrow, granulocytic sarcoma: immunohistochemical staining for myeloperoxidase using NCL-MYELO. Note intense cytoplasmic staining of malignant myeloid cells. Paraffin section.

Antigen Background

Myeloperoxidase is a lysosomal enzyme found in cells of the myeloid series which metabolizes most of the hydrogen peroxide generated by activated phagocytes. It is a major constituent of azurophilic cytoplasmic granules that uses hydrogen peroxide to oxidize a variety of aromatic compounds and chloride ions to hypochlorous acid (HOCI), a strong oxidant. HOCI is the most bacteriocidal oxidant known to be produced by neutrophils. HOCI reacts with proteins to form cytotoxic chloramines. Myeloperoxidase is reported to be a major component in all myeloid cells, including mature granulocytes and is a superior marker to myeloperoxidase mRNA, whose level decreases with the maturation of the cell and is not detectable from the myelocyte stage onwards. Myeloperoxidase is reported to be expressed in neutrophil granulocytes and monocytes in blood, in precursors of granulocytes in the bone marrow and in Kupffer cells of the liver.


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Code Name Configuration Use Datasheet MSDS Qty
PA0491 7ml Myeloperoxidase BondRTU Pr Bond ready to use reagent P(HIER) Info MSDS
MYELO-L-U 1ml NCL-L-MYELO Liquid Concentrated Monoclonal Antibody P Info MSDS
MYELO-S 0.1ml NCL-MYELO Lyophilised Concentrated Monoclonal Antibody P Info MSDS
MYELO-U 1ml NCL-MYELO US IVD Lyophilised Concentrated Monoclonal Antibody P Info MSDS
MYELO 1ml NCL-MYELO Lyophilised Concentrated Monoclonal Antibody P Info MSDS