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Myelin Basic Protein Primary Antibodies

Myelin Basic Protein Novocastra

Human spinal cord, cervical: immunohistochemical staining for myelin basic protein using NCL-MBP. Note cytoplasmic staining of cells in white matter. Paraffin section.
Human spinal cord, cervical: immunohistochemical staining for myelin basic protein using NCL-MBP. Note cytoplasmic staining of cells in white matter. Paraffin section.

Antigen Background

Myelin basic protein is reported to account for about 30 percent of the proteins in myelin found in the central nervous system. It can induce experimental allergic encephalomyelitis (EAE), a T-lymphocyte mediated disease due to delayed-type hypersensitivity; though each animal species appears to respond to a different fragment of the 170 amino acid polypeptide. Four different isoforms have been identified through cDNA cloning. All four of these variants are identical except for the insertion or deletion of two peptide fragments encoded by exons 2 and 5. Myelin basic protein is reported to be expressed in oligodendrocytes, myelin of white matter in the brain and spinal cord, and in peripheral nerves, though it is expressed less abundantly in gray matter.

Product Specific Information

NCL-MBP was raised to guinea pig myelin basic protein and is reactive with human myelin basic protein.


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CLONE: 7H11

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Code Name Configuration Use Datasheet MSDS Qty
MBP 1ml NCL-MBP Lyophilised Concentrated Monoclonal Antibody P(HIER) Info MSDS
MBP-S 0.1ml NCL-MBP Lyophilised Concentrated Monoclonal Antibody P(HIER) Info MSDS