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Multiple Myeloma Oncogene 1 (MUM-1) Primary Antibodies

Multiple Myeloma Oncogene 1 (MUM-1)

Human diffuse large B cell lymphoma: immunohistochemical staining for multiple myeloma oncogene 1 (MUM-1) using NCL-L-MUM1. Paraffin section.
Human diffuse large B cell lymphoma: immunohistochemical staining for multiple myeloma oncogene 1 (MUM-1) using NCL-L-MUM1. Paraffin section.

Antigen Background

The MUM-1 (multiple myeloma oncogene 1) gene was originally identified because of its involvement in the t(6:14) translocation observed in multiple myeloma, which causes the juxtaposition of the MUM-1 gene to the Ig heavy chain locus. MUM-1 is expressed in late plasma cell directed stages of B cell differentiation and in activated T cells, suggesting that MUM-1 may serve as a marker for lympho-hemopoietic neoplasms derived from these cells. The morphologic spectrum of MUM-1 expressing cells has been found to range from that of a centrocyte to that of a plasmablast/plasma cell. Consequently the histogenic value of MUM-1 may be to provide a marker to aid in the identification of the transition from BCL-6 positive (germinal center B cells) to CD138 positive (immunoblasts and plasma cells).

 

 


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CLONE: EAU32

Material with code "MUM-1" is discontinued , possible alternatives:

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Code Name Configuration Use Datasheet MSDS Qty
PA0129 7ml MUM1 Bond RTU Primary Bond ready to use reagent P(HIER) Info MSDS
MUM1-L 1ml NCL-L-MUM1 Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS
MUM1-L-CE-S 0.1ml NCL-L-MUM1 Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS
MUM1-L-CE 1ml NCL-L-MUM1 Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS
MUM1-L-S 0.1ml NCL-L-MUM1 Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS