Warning! You won't be able to use the quotation basket until you enable cookies in your Web browser.
Warning! Your Web browser is no longer supported. Please upgrade to a modern browser.
Microphthalmia Transcription Factor (MITF) Primary Antibodies

Microphthalmia Transcription Factor (MITF) Novocastra

Human malignant melanoma: immunohistochemical staining for microphthalmia transcription factor using NCL-L-MITF. Note nuclear staining of melanoma cells. Paraffin section.
Human malignant melanoma: immunohistochemical staining for microphthalmia transcription factor using NCL-L-MITF. Note nuclear staining of melanoma cells. Paraffin section.

Antigen Background

Microphthalmia transcription factor (MITF) gene product, a nuclear transcription factor of the basic-helix-loop-helix type, is thought to play a role in the regulation of genes encoding the enzymes necessary for melanogenesis. These include tyrosinase, TRP-1 and TRP-2. MITF is critical for the embryonic development and postnatal viability of melanocytes. The melanocyte-specific isoform of microphthalmia transcription factor MITF-M, is reported to be expressed in normal and malignant melanocytes. The other isoforms, MITF-A, MITF-C and MITF-H, differ structurally at the N-terminus from MITF-M.

Product Specific Information

Clone 34CA5 is reported to be reactive with the MITF-M isoform.


loading...

CLONE: 34CA5

Material with code "MITF" is discontinued , possible alternatives:

Request a quote

Code Name Configuration Use Datasheet MSDS Qty
MITF-L 1ml NCL-L-MITF Liquid Concentrated Monoclonal Antibody F, P(HIER) Info MSDS
MITF-S 0.1ml NCL-MITF Lyophilised Concentrated Monoclonal Antibody F, P(HIER) Info MSDS
MITF 1ml NCL-MITF Lyophilised Concentrated Monoclonal Antibody F, P(HIER) Info MSDS