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Mesothelin Primary Antibodies

Mesothelin Novocastra

Human mesothelioma: immunohistochemical staining for mesothelin using NCL-MESO.  Note intense membrane staining of tumor cells. Paraffin section.
Human mesothelioma: immunohistochemical staining for mesothelin using NCL-MESO. Note intense membrane staining of tumor cells. Paraffin section.

Antigen Background

Mesothelin is a glycosyl-phosphatidylinositol-linked (GPI) glycoprotein of 40kD present on the surface of mesothelial cells, mesotheliomas, epithelial ovarian cancers and some squamous cell carcinomas. It is synthesized as a 69 kD precursor which is enzymatically processed into an N-terminal secreted form of 30 kD and the GPI-linked membrane-bound form of 40 kD. The secreted form is identical to the megakaryocyte potentiating factor, but it is the GPI-linked membrane-bound form which has generated interest. Mesothelin is abundantly expressed in the kidney and in occasional epithelial cells of the trachea, tonsil and fallopian tube. The function of mesothelin is unclear but it may have a role in cellular adhesion. Mesothelin is reported to be abundant in the normal mesothelial cells from which malignant mesotheliomas and ovarian cystadenocarcinomas are derived.


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Code Name Configuration Use Datasheet MSDS Qty
PA0373 7ml Mesothelin Bond RTU Primary Bond ready to use reagent P(HIER) Info MSDS
MESO-L-CE 1ml NCL-L-MESO Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS
MESO-L 1ml NCL-L-MESO Liquid Concentrated Monoclonal Antibody F, P(HIER) Info MSDS
MESO-CE 1ml NCL-MESO Lyophilised Concentrated Monoclonal Antibody P(HIER) Info MSDS
MESO-CE-S 0.1ml NCL-MESO Lyophilised Concentrated Monoclonal Antibody Info MSDS
MESO-S 0.1ml NCL-MESO Lyophilised Concentrated Monoclonal Antibody F, P(HIER) Info MSDS
MESO 1ml NCL-MESO Lyophilised Concentrated Monoclonal Antibody F, P(HIER) Info MSDS
MESO-R-7-CE 7ml RTU-MESO Ready to Use Monoclonal Antibody P(HIER) Info MSDS