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Immunoglobulin G Primary Antibodies

Immunoglobulin G

Human myeloma: note immunohistochemical staining of malignant tumor cells with PA0905 (clone RWP49). Paraffin section.
Human myeloma: note immunohistochemical staining of malignant tumor cells with PA0905 (clone RWP49). Paraffin section.

Antigen Background

The human immunoglobulins consist of two identical heavy chains (~50 kD) and two identical light chains, which are linked together by disulphide bonds. The light chains can be either kappa or lambda. The five immunoglobulins IgA, IgD, IgE, IgG and IgM differ in their heavy chains, and IgA and IgM differ as they can occur in polymeric forms. The heavy chain of IgG is named the gamma-chain. In humans, IgG consists of four sub classes that differ only marginally in their amino acid composition. Antibodies to IgG have been reported to be useful in the identification of plasma cells, lymphoid cells containing IgG and classifying B cell derived neoplasms. The normal B cell population is polyclonal, expressing a range of different immunoglobulins. In contrast, the majority of B cell neoplasms are characterized by the proliferation of monoclonal cells expressing one type of light chain, whereas more than one type of heavy chain can be expressed by the same cell. 


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CLONE: RWP49

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Code Name Configuration Use Datasheet MSDS Qty
PA0905 7ml Immunoglobulin G Bond RTU Primary Bond ready to use reagent Info MSDS
IGG-L 1ml NCL-L-IgG Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS
IGG-L-S 0.1ml NCL-L-IgG Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS
IGG-L-CE-S 0.1ml NCL-L-IgG Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS
IGG-L-CE 1ml NCL-L-IgG Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS