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Human Chorionic Gonadotrophin (beta) Primary Antibodies

Human Chorionic Gonadotrophin (beta) Novocastra

Antigen Background

Human chorionic gonadotrophin (hCG) is a glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. hCG is composed of two subunits, alpha and beta. The alpha subunit of hCG is identical to the subunit of luteinising hormone, thyroid stimulating hormone and follicle stimulating hormone. The common alpha chain and the hormone-specific beta chains have molecular weights of 14 kD and 17 kD, respectively.The hCG beta-subunit is unique in the family of beta-containing glycoprotein hormones in that it contains an extension of 29 amino acids at its COOH end. It is believed that the C-terminal region of the HCG-beta subunit plays a role in the intracellular behavior of the heterodimer.

Product Specific Information

NCL-HCGp was raised to the isolated beta-chain of human chorionic gonadotrophin and reacts with placental trophoblasts. NCL-HCGp shows a slight cross-reaction with luteinising hormone and may, therefore, stain basophil cells in the pituitary.


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CLONE: POLYCLONAL

Material with code "HCG (BETA)" is discontinued , possible alternatives:

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Code Name Configuration Use Datasheet MSDS Qty
PA0014 7ml HCG Bond RTU Primary Bond ready to use reagent P(HIER) Info MSDS
HCGP 1ml NCL-HCGp Lyophilised Polyclonal F, P(ENZYME) Info
HCGP-U 1ml NCL-HCGp US IVD Lyophilised Polyclonal F, P(ENZYME) Info MSDS