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HLA Class II (DR) Antigen Primary Antibodies

HLA Class II (DR) Antigen Novocastra

Human anaplastic lymphoma: immunohistochemical staining for HLA class II antigen using NCL-LN3. Note membrane staining of large cells. Paraffin section.
Human anaplastic lymphoma: immunohistochemical staining for HLA class II antigen using NCL-LN3. Note membrane staining of large cells. Paraffin section.

Antigen Background

HLA-DR is an MHC Class II antigen that maps to chromosome 6. It is a heterodimer composed of 2 non-covalently associated glycoproteins of about 35 kD (alpha, heavy) and 27 kD (beta, light).Both chains are comprised of two Ig-like domains and have transmembrane sequences and short cytoplasmic tails. It is reported to be expressed mainly on antigen-presenting cells (monocytes/macrophages and dendritic cells), B cells and some activated T cells. Expression has also been reported on thymic epithelial cells.


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Code Name Configuration Use Datasheet MSDS Qty
LN3-S 0.1ml NCL-LN3 Lyophilised Concentrated Monoclonal Antibody F, P Info MSDS
LN3-U 1ml NCL-LN3 US IVD Lyophilised Concentrated Monoclonal Antibody F, P Info MSDS