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DOG-1 Primary Antibodies

DOG-1

Human gastrointestinal stromal tumor: immunohistochemical staining for DOG-1 using  NCL-L-DOG-1. Note intense membrane and cytoplasmic staining of tumor cells. Paraffin section.
Human gastrointestinal stromal tumor: immunohistochemical staining for DOG-1 using NCL-L-DOG-1. Note intense membrane and cytoplasmic staining of tumor cells. Paraffin section.

Antigen Background

DOG-1, a 986 amino acid protein of unknown function, is expressed predominantly on the plasma membrane of gastrointestinal stromal tumors (GISTs) and is rarely expressed in other soft tissue tumors, which, due to appearance, can be confused with GISTs. Reactivity for DOG-1 has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha mutants that fail to express KIT antigen.

Product Specific Information

The use of PBS-based diluents may result in increased background staining.


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Code Name Configuration Use Datasheet MSDS Qty
PA0219 7ml DOG-1 Bond RTU Primary Bond ready to use reagent P(HIER) Info MSDS
DOG-1-L-CE 1ml NCL-L-DOG-1 Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS
DOG-1-L 1ml NCL-L-DOG-1 Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS
DOG-1-L-S 0.1ml NCL-L-DOG-1 Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS