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Cyclin B1 Primary Antibodies

Cyclin B1 Novocastra

Human breast carcinoma: immunohistochemical staining for cyclin B1 using NCL-CYCLIN B1. Note cytoplasmic staining of tumor cells. Paraffin section.
Human breast carcinoma: immunohistochemical staining for cyclin B1 using NCL-CYCLIN B1. Note cytoplasmic staining of tumor cells. Paraffin section.

Antigen Background

Cyclin B protein acts in a similar way to cyclin A, as regulatory subunits of p34/cdc2/cdk1 affecting the G2 to M phase transition. Cyclin B expression is, therefore, restricted to a specific short period of the cell cycle with cyclin B1 expression detected earlier and peaking in concentration before cyclin B2 expression. Cyclin B positive cells, indicated by cytoplasmic staining, in proliferating tissue are reported to represent a subset of Ki67 positive cells.

Product Specification Information

Please note that methacarn fixation produces optimal staining.


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CLONE: 7A9

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Code Name Configuration Use Datasheet MSDS Qty
CYCLINB1-S 0.1ml NCL-CYCLIN B1 Lyophilised Concentrated Monoclonal Antibody C, P(HIER), W Info MSDS
CYCLINB1-U 1ml NCL-CYCLIN B1 US IVD Lyophilised Concentrated Monoclonal Antibody C, P(HIER), W MSDS