CD63 (Melanoma Marker) Novocastra
CD63 antigen is a member of the TM4 superfamily with its structure consisting of four transmembrane regions, short cytoplasmic N and C-termini and two extracellular regions. CD63 antigen is widely distributed on the surface and interior of both hematopoietic and non-hematopoietic cells such as most sweat glands, islets of Langerhans, pituitary, pancreas, peribronchial glands, Paneth cells and prostate glands. It is reported to be strongly expressed on monocytes, macrophages and activated platelets and weakly expressed on lymphocytes and granulocytes. CD63 antigen associates non-covalently with CD9, CD81 and the integrins VLA-3, VLA-4 and VLA-6. It is reported that CD63 antigen may play a role as a tumor suppressor gene, as its expression in human melanoma cells reduces tumor spread and metastasis.
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|CD63-L-U||1ml NCL-L-CD63||Liquid Concentrated Monoclonal Antibody||P||Info||MSDS||
|CD63||1ml NCL-CD63||Lyophilised Concentrated Monoclonal Antibody||F, P||Info||MSDS||
|CD63-U||1ml NCL-CD63 US IVD||Lyophilised Concentrated Monoclonal Antibody||F, P||MSDS||
|CD63-S||0.1ml NCL-CD63||Lyophilised Concentrated Monoclonal Antibody||F, P||Info||MSDS||