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CD44 Variant Antibodies Primary Antibodies

CD44 Variant Antibodies Novocastra

Human squamous cell carcinoma, floor of the mouth: immunohistochemical staining for CD44 variant 3 using NCL-CD44v3. Note intense membrane staining of tumor cells. Paraffin section.
Human squamous cell carcinoma, floor of the mouth: immunohistochemical staining for CD44 variant 3 using NCL-CD44v3. Note intense membrane staining of tumor cells. Paraffin section.

Antigen Background

The CD44 molecule belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial and hemopoiesis tissues. CD44 is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (H-CAM) molecule. The additional 10 exons (v1 to v10) are only expressed by alternative splicing of the nuclear RNA. The expression of specific cell adhesion molecule CD44 splice variants has been reported to be associated with metastasis in certain human malignancies.


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CLONE: VFF-8

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Code Name Configuration Use Datasheet MSDS Qty
CD44V5 1ml NCL-CD44v5 Lyophilised Concentrated Monoclonal Antibody F, P(HIER) Info MSDS