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Carbonic Anhydrase IX Primary Antibodies

Carbonic Anhydrase IX Novocastra

Human stomach: immunohistochemical staining for carbonic anhydrase IX using NCL-L-CAIX. Note intense membrane and cytoplasmic staining of the mucus secreting cells of the deep glands. Paraffin section.
Human stomach: immunohistochemical staining for carbonic anhydrase IX using NCL-L-CAIX. Note intense membrane and cytoplasmic staining of the mucus secreting cells of the deep glands. Paraffin section.

Antigen Background

Carbonic anhydrase (CA) is an enzyme that assists rapid interconversion of carbon dioxide and water into carbonic acid, protons, and bicarbonate ions. Originally named MN/G250, carbonic anhydrase IX (CAIX) is a cell surface transmembrane protein, which is predominantly found in the gastrointestinal tract and gall bladder. The glandular regions of normal colon are reported to be negative, but in the case of adenocarcinoma, the glands are positive. CAIX is also reported to be expressed in common epithelial tumors such as carcinomas of the esophagus, lung, colon, kidney, cervix and non-small cell lung carcinoma.In breast carcinomas, CAIX expression has been reported to be associated with malignant tissue. Expression of CAIX is reported to be absent in normal kidney, chromophobe carcinomas or oncocytomas, however, it is specifically expressed in clear cell renal carcinomas.


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Code Name Configuration Use Datasheet MSDS Qty
CAIX-L-CE 1ml NCL-L-CAIX Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS
CAIX-L-CE-S 0.1ml NCL-L-CAIX Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS
CAIX-L-S 0.1ml NCL-L-CAIX Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS
CAIX-L 1ml NCL-L-CAIX Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS