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CA19-9 (Sialyl Lewis a) Primary Antibodies

CA19-9 (Sialyl Lewis a) Novocastra

Normal human colon: immunohistochemical staining for Sialyl Lewis antigen using NCL-L-CA19-9. Note extracellular-associated staining of colonic epithelial cells. Paraffin section.
Normal human colon: immunohistochemical staining for Sialyl Lewis antigen using NCL-L-CA19-9. Note extracellular-associated staining of colonic epithelial cells. Paraffin section.

Antigen Background

CA19-9 is an epitope on the sialylated Lewisa carbohydrate structure. Sialylated Lewisa plays a role in cell adhesion by acting as a functional ligand for the inducible adhesion molecule E-selectin. CA19-9 and CA50 (carcinoma associated mucin antigen) are useful serum markers in the diagnosis and follow up of gastrointestinal and pancreatic cancers. In carcinoma of the pancreas, it is reported that the immunohistochemical expression of both CA19-9 and CA50 correlates with tumor differentiation where the strongest staining is observed in well differentiated tumors.These two markers are also reported in a number of benign lesions such as chronic pancreatitis.

Product Specific Information

Clone C241:5:1:4 reacts specifically with Sialyl Lewisa - containing glycolipids, showing no crossreaction with Lewisa, Lewisb, or other structurally related molecules. The epitope recognized by NCL-L-CA19-9 is designated CA19-9 and is similar to CA50 (carcinoma associated mucin antigen).


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CLONE: C241:5:1:4

Material with code "CA19-9" is discontinued , possible alternatives:

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Code Name Configuration Use Datasheet MSDS Qty
PA0424 7ml CA19-9 Bond RTU Primary Bond ready to use reagent P(HIER) Info MSDS
CA19-9-L 1ml NCL-L-CA19-9 Liquid Concentrated Monoclonal Antibody F, P(HIER) Info
CA19-9 1ml NCL-CA19-9 Lyophilised Concentrated Monoclonal Antibody F, P(HIER) Info MSDS