B Cell Specific Octamer Binding Protein1 (BOB-1)
B cell specific octamer binding protein-1 (BOB-1), also known as OBF-1 and OCA-B, is a lymphocyte specific transcriptional coactivator protein. It interacts with OCT1 and OCT2 transcription factors and contributes to the transcriptional activity of octamer motifs.
BOB-1 has been reported to be detectable in all B cell populations found in reactive lymphoid tissues. The strongest expression being found in germinal center B cells and plasma cells.
The expression of BOB-1 in B cell tumors has been reported to be variable.
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|PA0558||7ml BOB-1 Bond RTU Primary|