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Gross Cystic Disease Fluid Protein-15 Novocastra HD

Gross Cystic Disease Fluid Protein-15

Invasive Breast Carcinoma. Cytoplasmic staining in tumor cells. Paraffin section.
Invasive Breast Carcinoma. Cytoplasmic staining in tumor cells. Paraffin section.

Antigen Background

Gross cystic disease of the breast is a benign premenopausal disorder in which cysts are a predominant pathological lesion. These cysts appear to be formed from excessive apocrine cystic secretions. This fluid is composed of several glycoproteins including a unique 15 kD monomer protein, GCDFP15. It has been reported that cytosolic analysis of normal tissue from all major organs has demonstrated GCDFP15 in apocrine epithelia, lacrimal, ceruminous and Moll's glands and in numerous serous cells of the submandibular, tracheal, bronchial, sublingual and minor salivary glands. Cytosol from breast carcinoma lesions are reported to contain GCDFP15 at a wide range of concentrations. The concentration is reported to be highest in more differentiated carcinomas and GCDFP15 shows only a few positive individual epithelial cells within lobules and small ducts in normal breast. Expression has also been reported in fibroadenomas within areas of apocrine metaplasia.


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Code Name Configuration Use Datasheet MSDS Qty
PA0708 7ml GCDFP15 Bond RTU Primary Bond ready to use reagent P(HIER) Info MSDS
GCDFP15-L 1ml NCL-L-GCDFP15 Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS
GCDFP15-L-S 0.1ml NCL-L-GCDFP15 Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS
GCDFP15-L-CE-S 0.1ml NCL-L-GCDFP15 Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS
GCDFP15-L-CE 1ml NCL-L-GCDFP15 Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS