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Cytokeratin 20 Novocastra HD

Cytokeratin 20

CK20, clone Ks20.8, Human Colon. Click to view under virtual microscope.
CK20, clone Ks20.8, Human Colon. Click to view under virtual microscope.

Antigen Background

Cytokeratin 20 has been demonstrated to be almost entirely confined to the gastric and intestinal epithelium, urothelium and Merkel cells of the skin. Cytokeratin 20 is less acidic than other type I cytokeratins and is of interest due to its restricted tissue expression. In normal tissue, cytokeratin 20 is expressed in intestinal epithelium, gastric foveolar epithelium, a number of endocrine cells in the upper portions of the pyloric glands, urothelium and Merkel cells in epidermis. In tumors it is reported, there is a marked difference in the expression of cytokeratin 20 within different carcinomas. Neoplasms expressing cytokeratin 20 are derived from normal epithelia which themselves expressed cytokeratin 20. Colorectal carcinomas consistently express cytokeratin 20, while gastric adenocarcinomas express cytokeratin 20 to a lesser degree Adenocarcinomas of the gall bladder and bile duct, ductal cell adenocarcinomas of the pancreas, mucinous ovarian tumors, Merkel cell tumors and transitional cell carcinomas have also been reported to express cytokeratin 20. 


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CLONE: KS20.8

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Code Name Configuration Use Datasheet MSDS Qty
PA0037 30ml Cytokeratin 20 Bond RTU Primary Bond ready to use reagent P(HIER) Info MSDS
PA0022 7ml Cytokeratin 20 Bond RTU Primary Bond ready to use reagent P(HIER) Info MSDS
CK20-L-CE-H 0.5ml NCL-L-CK20 Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS
CK20-L-S 0.1ml NCL-L-CK20 Liquid Concentrated Monoclonal Antibody P(HIER), W Info MSDS
CK20-L-CE-S 0.1ml NCL-L-CK20 Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS
CK20-L-H 0.5ml NCL-L-CK20 Liquid Concentrated Monoclonal Antibody P(HIER), W Info MSDS
CK20-L 1ml NCL-L-CK20 Liquid Concentrated Monoclonal Antibody P(HIER), W Info MSDS
CK20-L-CE 1ml NCL-L-CK20 Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS